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NMA Today: Transforming Evidence Synthesis for Smarter Clinical Decision Making

If you're frustrated with the challenges of outsourcing critical evidence synthesis work — like limited control, lack of flexibility, long timelines, and increasing costs — we understand your concerns. While outsourcing can provide necessary expertise, we believe there's a better way to manage the process, giving you more control without completely removing the value that vendors bring. Our solution is designed to help you strike the right balance.

The outsourcing dilemma

Pharmaceutical companies, especially HTA departments, often face significant challenges when outsourcing evidence synthesis:

  • Limited Control
    Outsourcing means you lose direct control over the synthesis process, making real-time adjustments difficult. You’re often dependent on external vendors' timelines and processes.
  • Lack of Flexibility
    Vendors often follow rigid procedures that may not fully align with your unique project needs, limiting the level of customization available.
  • Missed Learning Opportunities
    Outsourcing often means your team isn't involved in the intricacies of the process, missing the chance to build internal expertise in evidence synthesis and related methodologies.
  • Rising Costs
    Outsourcing multiple evidence syntheses can lead to rapidly increasing costs, especially when the same processes are repeated across different projects.

Our solution addresses these pain points while still allowing you to leverage vendor expertise where necessary. With increased control, flexibility, and opportunities for learning, you’ll be empowered to make the most of your evidence synthesis efforts—without completely eliminating the need for vendors.

Your Solution: In-House Mastery

If you're frustrated by the limitations of outsourcing critical evidence synthesis — such as limited control, lack of flexibility, long timelines, and escalating costs — we offer a transformative alternative. Our solution combines cutting-edge software with expert consultancy to give you control over the entire evidence synthesis process while maintaining access to high-level vendor expertise where needed.

We provide a web-based application, designed specifically for conducting Network Meta-Analysis (NMA) and Indirect Treatment Comparisons (ITC). This software, combined with our consultancy expertise, empowers your team to conduct evidence synthesis in-house, offering enhanced control, flexibility, and cost efficiency.

The Benefits

Our solution offers a game-changing alternative to the typical challenges of outsourcing evidence synthesis. By partnering with us, you gain key advantages that enhance your control, flexibility, and efficiency, through a seamless combination of advanced software tools and expert consultancy.

  • Cost Savings
    Rather than continually outsourcing, we empower you to bring evidence synthesis in-house. This strategic shift reduces long-term costs, allowing you to invest your budget more efficiently across projects.
  • Complete Control
    Our solution grants you full autonomy over the evidence synthesis process. You can seamlessly implement our tools within your existing ecosystem, allowing for easy integration with your current workflows and systems. This means you can fine-tune every aspect of the synthesis process in real time, ensuring alignment with your specific requirements, timelines, and internal protocols.
  • Enhanced Flexibility
    Our tools and processes are fully customizable, allowing you to tailor the evidence synthesis to meet the specific objectives of your department. No more rigid, one-size-fits-all vendor processes.
  • Knowledge Empowerment with Expert Support
    We provide more than just software — we empower your team through knowledge transfer and expert guidance. Our solution equips your team with the in-depth expertise needed to master evidence synthesis methods and processes, enabling you to confidently lead future projects in-house. In addition, our Expert Consulting Support offers hands-on assistance in fine-tuning your Network Meta-Analysis (NMA) processes and interpreting complex results. With this combination of knowledge transfer and expert consulting, your team can navigate intricate data challenges, optimize in-house capabilities, and produce high-quality, impactful results.
Features That Make the Difference

Our solution is packed with features designed to simplify your evidence synthesis journey:

  • Automated Report Generation with AI-Powered Compliance Review
    Save time and resources by automating the creation of comprehensive reports. Not only can you make adjustments to the analysis or key assumptions at any point in the process, with the report automatically reflecting the changes, but our AI also reviews the reports for compliance with conduct and reporting guidelines. This includes adherence to standards set by the Directorate-General for Health and Food Safety, NICE, and EUNETHTA, ensuring your reports always contain the most up-to-date, accurate, and fully compliant information without having to start from scratch.
  • Seamless Integration and Privacy Assurance:
    Our software fully integrates into your existing systems, providing a hassle-free and efficient solution for your evidence synthesis needs. All your data remains securely within your company, ensuring complete privacy and data control. Alternatively, we offer the option to host your data in a secure cloud system with access enabled via VPN, offering flexibility while maintaining the highest levels of security.
  • Streamlined Data Import and Retrieval
    Effortlessly enhance your evidence synthesis process by importing Systematic Literature Review (SLR) results (e.g., a spreadsheet prepared by the vendor) and automatically retrieving trial information from the clinicaltrials.gov database. This combined approach helps refine review questions, identify meaningful comparators, and improve the overall accuracy of your synthesis.
  • Customizable and User-Friendly Interface
    Tailor every aspect of the synthesis to meet your specific needs and project objectives with our highly customizable parameters, all within an intuitive, user-friendly interface that ensures effortless navigation for you and your team.
  • Access to Extensive Training Materials
    Gain a competitive edge with a comprehensive library of training materials prepared by industry professionals. These resources empower your team to master evidence synthesis techniques and stay at the forefront of industry best practices.
Key Features
Import Results from the SLR
Automated Data retrieval
Network Meta-Analysis
Automated Report Generation
Compliance with HTA guidelines
User-Friendly Interface
Highly Customizable Parameters
Privacy Assurance
Fully Embedded Software
Access to Extensive Training Materials
Testimonials

Thomas initially joined us as an methodological expert in treatment comparisons, but quickly became an integral part of our team. His expertise and commitment were instrumental in delivering high-quality outcomes on time, and his collaborative approach ensured universal satisfaction.

Principal Biostatistician, Drug Sponsor

Thomas never missed a detail and was always open to feedback, demonstrating a level of completeness and thoroughness that is rare. His ability to accommodate different perspectives while maintaining the highest standards of quality made him one of the best biostatisticians I have ever worked with.

Senior HEOR & RWE Manager, Drug Sponsor

I particularly enjoyed Thomas’s innovative approach and the fresh ideas he consistently brought to the table. He had a unique ability to challenge the status quo, always pushing for better solutions and deeper insights. His skills in statistics and applied statistical models are top-notch, and his ability to contextualize these models within the broader scope of clinical trials was exceptional.

Senior HEOR & RWE Manager, Drug Sponsor

One of Thomas's standout qualities is his ability to understand and communicate complex statistical and medical concepts clearly. His ability to summarise results for the dossier team during appraisal meetings was particularly noteworthy, and stakeholders consistently praised his work.

Lead Biostatistician, Drug Sponsor

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